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Morula Stage Embryo

In Vitro Fertilization Picture of a Morula Stage Embryo - Day 4 Human IVF Embryo

  • A morula contains about 10 - 30 cells
  • The morula stage is the final stage prior to formation of a fluid filled cavity called the blastocoel cavity
  • Once the cavitation has occurred, we can see the fluid in the cavity between the cells and we call the embryo an early blastocyst
  • Although morula stage embryos are usually seen on day 4 and blastocysts are usually seen on day 5, sometimes we have only morulas on day 5
  • In that case, we do not know if the embryos are slower than average because they are weaker, or because they are healthy but just developing slower than average
  • Transferring morulas on day 5 results in a reasonable pregnancy rate, although it is not as high as the pregnancy rate with blastocyst transfer on day 5

Embryo arrest at the morula stage is not uncommon, which is one reason that transfer at the blastocyst stage can be a beneficial IVF treatment strategy.

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